Sleep disorder associated with antibodies to IgLON5: parasomnia or agrypnia?

Sleep disorder associated with antibodies to IgLON5: parasomnia or agrypnia?

Sleep disorder associated with antibodies to IgLON5: parasomnia or agrypnia?-Authors' reply.

We read with great interest the paper by Lidia Sabater and colleagues, who describe a novel neuroimmuno logical disease that is a complex, severe sleep disorder associated with antibodies to IgLON5. We have noted a clinically similar disorder in a single patient who had serum and CSF antibodies to the metabotropic GABAB receptor. Similar to the patients in Sabater and colleagues’ report, our pa...

Sleep disorder, chorea, and dementia associated with IgLON5 antibodies

A novel syndrome characterized by a distinctive sleep disorder accompanied by variable symptoms of brainstem involvement and a highly restricted haplotype was recently described in association with antibodies to a neuronal cell adhesion protein named IgLON5. Because of the symptoms and chronic disease progression, most of these patients are primarily seen by specialists in sleep and neurodegene...

A novel NREM and REM parasomnia with sleep breathing disorder associated with antibodies against IgLON5: a case series, pathological features, and characterization of the antigen

Lidia Sabater, PhD1,*, Carles Gaig, MD1,2,3,*, Ellen Gelpi, MD1,4,*, Luis Bataller, MD5,7, Jan Lewerenz, MD6, Estefanía Torres-Vega, BSc7, Angeles Contreras, MD8, Bruno Giometto, MD9, Yaroslau Compta, MD2, Cristina Embid, MD3,10, Isabel Vilaseca, MD3,11, Alex Iranzo, MD1,2,3, Joan Santamaría, MD1,2,3, Josep Dalmau, MD1,12,13, and Francesc Graus, MD1,2 1Institut d'Investigacions Biomèdiques Augu...

Sexsomnia: parasomnia associated with sexual behaviour during sleep.

INTRODUCTION The purpose of our study is to describe 4 cases of sexsomnia, a form of parasomnia characterised by sexual behaviour during sleep. METHODS Clinical history and video-polysomnography recordings from patients diagnosed with sexsomnia in the Multidisciplinary Sleep Unit at Hospital Clínic in Barcelona. RESULTS Three men and one woman between 28 and 43 years of age reported sexual ...